{"id":17947,"date":"2021-06-28T16:19:54","date_gmt":"2021-06-28T13:19:54","guid":{"rendered":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911.jpg"},"modified":"2021-06-28T16:25:20","modified_gmt":"2021-06-28T13:25:20","slug":"screenshot_20210628_161911","status":"inherit","type":"attachment","link":"https:\/\/yaronmargolin.com\/?attachment_id=17947","title":{"rendered":"Screenshot_20210628_161911"},"author":1,"comment_status":"open","ping_status":"closed","template":"","meta":[],"description":{"rendered":"<p class=\"attachment\"><a href='https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911.jpg'><img width=\"300\" height=\"202\" src=\"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-300x202.jpg\" class=\"attachment-medium size-medium\" alt=\"\" decoding=\"async\" srcset=\"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-300x202.jpg 300w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-768x518.jpg 768w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-100x67.jpg 100w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-150x101.jpg 150w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-200x135.jpg 200w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-450x304.jpg 450w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-600x405.jpg 600w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-900x607.jpg 900w, https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911.jpg 981w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n"},"caption":{"rendered":"<p>\u05e4\u05e2\u05d5\u05dc\u05d5\u05ea \u05e4\u05dc\u05d9\u05d0\u05d5\u05d8\u05e8\u05d5\u05e4\u05d9\u05d5\u05ea \u05e9\u05dc \u05d2\u05d5\u05e8\u05dd \u05d2\u05d3\u05d9\u05dc\u05d4 \u05e4\u05d9\u05d1\u05e8\u05d5\u05d1\u05dc\u05e1\u05d8\u05d9\u05dd 23 (FGF23).  FGF23 \u05de\u05d9\u05d5\u05e6\u05e8 \u05d1\u05e2\u05d9\u05e7\u05e8 \u05d1\u05e2\u05e6\u05dd \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d0\u05d5\u05e1\u05d8\u05d0\u05d5\u05d1\u05dc\u05e1\u05d8\u05d9\u05dd \u05d5\u05d0\u05d5\u05e1\u05d8\u05d0\u05d5\u05e6\u05d9\u05d8\u05d9\u05dd \u05d1\u05ea\u05e0\u05d0\u05d9\u05dd \u05e4\u05d9\u05d6\u05d9\u05d5\u05dc\u05d5\u05d2\u05d9\u05d9\u05dd.  \u05d4\u05e4\u05e8\u05e9\u05ea FGF23 \u05de\u05d2\u05d5\u05e8\u05d4 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05e4\u05d5\u05e1\u05e4\u05d8, \u05d4\u05d5\u05e8\u05de\u05d5\u05df \u05d4\u05e4\u05e8\u05ea\u05d9\u05e8\u05d5\u05d0\u05d9\u05d3 (PTH), \u05e6\u05d9\u05d8\u05d5\u05e7\u05d9\u05e0\u05d9\u05dd \u05d3\u05dc\u05e7\u05ea\u05d9\u05d9\u05dd, \u05d5\u05e2\u05dc \u05d9\u05d3\u05d9 \u05d4\u05d5\u05e8\u05de\u05d5\u05df \u05d5\u05d9\u05d8\u05de\u05d9\u05df D, 1a, 25-dihydroxyvitamin D 3, 1a, 25 (OH) 2 D 3. FGF23 \u05e4\u05d5\u05e2\u05dc \u05d1\u05d0\u05d5\u05e4\u05df \u05e2\u05e6\u05de\u05d0\u05d9 \u05e2\u05dc \u05d4\u05db\u05dc\u05d9\u05d4 \u05d4\u05e4\u05e8\u05d5\u05e7\u05e1\u05d9\u05de\u05dc\u05d9\u05ea \u05d5\u05d4\u05d3\u05d9\u05e1\u05d8\u05dc\u05d9\u05ea.  \u05e6\u05d9\u05e0\u05d5\u05e8\u05d5\u05ea.  \u05d1\u05e6\u05d9\u05e0\u05d5\u05e8\u05d9\u05d5\u05ea \u05db\u05dc\u05d9\u05d4 \u05e4\u05e8\u05d5\u05e7\u05e1\u05d9\u05de\u05dc\u05d9\u05d5\u05ea (PT), FGF23 \u05de\u05e2\u05db\u05d1 \u05e1\u05e4\u05d9\u05d2\u05d4 \u05d7\u05d5\u05d6\u05e8\u05ea \u05e9\u05dc \u05e4\u05d5\u05e1\u05e4\u05d8 \u05d5\u05d1\u05d9\u05d8\u05d5\u05d9 \u05e9\u05dc 1a-hydroxylase, \u05d4\u05d0\u05e0\u05d6\u05d9\u05dd \u05d4\u05de\u05d2\u05d1\u05d9\u05dc \u05d0\u05ea \u05d4\u05e7\u05e6\u05d1 \u05dc\u05d4\u05d5\u05e8\u05de\u05d5\u05df \u05d5\u05d9\u05d8\u05de\u05d9\u05df D, 1a, 25 (OH) 2 D 3, \u05e1\u05d9\u05e0\u05ea\u05d6\u05d4.  \u05d1\u05e6\u05d9\u05e0\u05d5\u05e8\u05d9\u05d5\u05ea \u05d3\u05d9\u05e1\u05d8\u05dc\u05d9\u05d5\u05ea (DT), FGF23 \u05de\u05d2\u05d1\u05d9\u05e8 \u05e1\u05e4\u05d9\u05d2\u05d4 \u05d7\u05d5\u05d6\u05e8\u05ea \u05e9\u05dc \u05e1\u05d9\u05d3\u05df \u05d5\u05e0\u05ea\u05e8\u05df.  \u05e1\u05e4\u05d9\u05d2\u05ea \u05e0\u05ea\u05e8\u05df \u05db\u05dc\u05d9\u05d9\u05ea\u05d9\u05ea \u05de\u05d5\u05d2\u05d1\u05e8\u05ea \u05e2\u05e9\u05d5\u05d9\u05d4 \u05dc\u05d4\u05e2\u05de\u05d9\u05e1 \u05e2\u05dc \u05d4\u05dc\u05d1 \u05e2\u05dc \u05d9\u05d3\u05d9 \u05e9\u05de\u05d9\u05e8\u05ea \u05e0\u05e4\u05d7 \u05d5\u05d9\u05ea\u05e8 \u05dc\u05d7\u05e5 \u05d3\u05dd \u05e9\u05dc\u05d0\u05d7\u05e8 \u05de\u05db\u05df.  \u05d4\u05d5\u05db\u05d7 \u05db\u05d9 FGF23 \u05de\u05e9\u05de\u05e9 \u05db\u05d2\u05d5\u05e8\u05dd \u05e4\u05e8\u05d5-\u05d4\u05d9\u05e4\u05e8\u05d8\u05e8\u05d5\u05e4\u05d9 \u05d9\u05e9\u05d9\u05e8 \u05d1\u05dc\u05d1.  \u05d1\u05e0\u05d5\u05e1\u05e3, \u05d4\u05dc\u05d1 \u05e2\u05e9\u05d5\u05d9 \u05dc\u05d4\u05e4\u05d5\u05da \u05dc\u05de\u05e7\u05d5\u05e8 \u05dc\u05de\u05d7\u05d6\u05d5\u05e8 FGF23 \u05d1\u05ea\u05e0\u05d0\u05d9\u05dd \u05e4\u05ea\u05d5\u05dc\u05d5\u05d2\u05d9\u05d9\u05dd \u05db\u05d2\u05d5\u05df \u05d0\u05d5\u05d8\u05dd \u05e9\u05e8\u05d9\u05e8 \u05d4\u05dc\u05d1 \u05d0\u05d5 \u05d4\u05d9\u05e4\u05e8\u05d8\u05e8\u05d5\u05e4\u05d9\u05d4 \u05e9\u05dc \u05d7\u05d3\u05e8 \u05e9\u05de\u05d0\u05dc.  \u05e2\u05d3\u05d5\u05d9\u05d5\u05ea \u05e2\u05d3\u05db\u05e0\u05d9\u05d5\u05ea \u05de\u05e6\u05d1\u05d9\u05e2\u05d5\u05ea \u05e2\u05dc \u05db\u05da \u05e9- FGF23 \u05de\u05e9\u05de\u05e9 \u05db\u05d5\u05d5\u05e1\u05ea \u05d0\u05d5\u05d8\u05d5\u05de\u05d8\u05d9 \/ \u05e4\u05e8\u05e7\u05e8\u05d9\u05df \u05dc\u05de\u05d9\u05e0\u05e8\u05dc\u05d9\u05d6\u05e6\u05d9\u05d4 \u05e9\u05dc \u05d4\u05e2\u05e6\u05dd \u05e2\u05dc \u05d9\u05d3\u05d9 \u05d3\u05d9\u05db\u05d5\u05d9 \u05e4\u05d5\u05e1\u05e4\u05d8\u05d0\u05d6 \u05d0\u05dc\u05e7\u05dc\u05d9\u05d9\u05df \u05d0\u05dc\u05e7\u05dc\u05d9\u05d9\u05df \u05dc\u05d0-\u05e1\u05e4\u05e6\u05d9\u05e4\u05d9 \u05d1\u05d0\u05d5\u05e1\u05d8\u05d0\u05d5\u05e6\u05d9\u05d8\u05d9\u05dd.  \u05e2\u05d3\u05d9\u05d9\u05df \u05dc\u05d0 \u05d1\u05e8\u05d5\u05e8 \u05d0\u05dd \u05dc\u05de\u05d7\u05d6\u05d5\u05e8 FGF23 \u05d9\u05e9 \u05d4\u05e9\u05e4\u05e2\u05d5\u05ea \u05d9\u05e9\u05d9\u05e8\u05d5\u05ea \u05e2\u05dc \u05db\u05dc\u05d9 \u05d4\u05d3\u05dd.  \u05d9\u05ea\u05e8 \u05e2\u05dc \u05db\u05df, \u05e8\u05d0\u05d9\u05d5\u05ea \u05de\u05ea\u05e4\u05ea\u05d7\u05d5\u05ea \u05de\u05e6\u05d9\u05e2\u05d5\u05ea \u05db\u05d9 FGF23 \u05e2\u05e9\u05d5\u05d9 \u05dc\u05e9\u05e0\u05d5\u05ea \u05d0\u05ea \u05ea\u05e4\u05e7\u05d5\u05d3\u05dd \u05e9\u05dc \u05ea\u05d0\u05d9 \u05de\u05e2\u05e8\u05db\u05ea \u05d4\u05d7\u05d9\u05e1\u05d5\u05df \u05d4\u05de\u05d5\u05dc\u05d3\u05ea.  \u05e4\u05e2\u05d5\u05dc\u05d5\u05ea \u05d4\u05db\u05dc\u05d9\u05d4 \u05e9\u05dc FGF23 \u05de\u05d7\u05d9\u05d9\u05d1\u05d5\u05ea \u05e0\u05d5\u05db\u05d7\u05d5\u05ea \u05e9\u05dc \u05d4\u05e7\u05d5\u05dc\u05d8\u05df \u05d4\u05de\u05e9\u05d5\u05ea\u05e3 a-Klotho \u05d1\u05e7\u05e8\u05d5\u05dd \u05ea\u05d0\u05d9 \u05d4\u05d9\u05e2\u05d3, \u05d5\u05d0\u05d9\u05dc\u05d5 \u05e4\u05e2\u05d5\u05dc\u05d5\u05ea \u05d4- FGF23 \u05e2\u05dc \u05e7\u05e8\u05d3\u05d9\u05d5\u05de\u05d9\u05d5\u05e6\u05d9\u05d8\u05d9\u05dd, \u05e2\u05e6\u05dd, \u05db\u05dc\u05d9 \u05d3\u05dd \u05d5\u05ea\u05d0\u05d9 \u05d7\u05d9\u05e1\u05d5\u05df \u05d0\u05d9\u05e0\u05df \u05ea\u05dc\u05d5\u05d9\u05d5\u05ea \u05d1\u05db\u05d5\u05ea\u05df \u05d5\u05dc\u05db\u05df \u05e2\u05e9\u05d5\u05d9\u05d5\u05ea \u05dc\u05d4\u05e4\u05d5\u05da \u05dc\u05e4\u05e2\u05d9\u05dc\u05d5\u05ea \u05e8\u05e7 \u05d1\u05d2\u05d5\u05d1\u05d4 \u05d2\u05d1\u05d5\u05d4.  \u05e8\u05d9\u05db\u05d5\u05d6\u05d9\u05dd \u05de\u05e7\u05d5\u05de\u05d9\u05d9\u05dd.<br \/>\n\u05de\u05e7\u05d5\u05e8 \u05d4\u05d0\u05d9\u05d5\u05e8 \u05d1\u05e6\u05d9\u05dc\u05d5\u05dd \u05de\u05e1\u05da \u05de\u05d4\u05de\u05d0\u05de\u05e8: Pleiotropic Actions of FGF23 \u05db\u05d0\u05df<\/p>\n<div class=\"read-more\"><a href=\"https:\/\/yaronmargolin.com\/?attachment_id=17947\">\u05e7\u05e8\u05d0 \u05e2\u05d5\u05d3 &#8250;<\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n"},"alt_text":"","media_type":"image","mime_type":"image\/jpeg","media_details":{"width":981,"height":662,"file":"2021\/06\/Screenshot_20210628_161911.jpg","sizes":{"medium":{"file":"Screenshot_20210628_161911-300x202.jpg","width":300,"height":202,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-300x202.jpg"},"thumbnail":{"file":"Screenshot_20210628_161911-150x150.jpg","width":150,"height":150,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-150x150.jpg"},"medium_large":{"file":"Screenshot_20210628_161911-768x518.jpg","width":768,"height":518,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-768x518.jpg"},"responsive-100":{"file":"Screenshot_20210628_161911-100x67.jpg","width":100,"height":67,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-100x67.jpg"},"responsive-150":{"file":"Screenshot_20210628_161911-150x101.jpg","width":150,"height":101,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-150x101.jpg"},"responsive-200":{"file":"Screenshot_20210628_161911-200x135.jpg","width":200,"height":135,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-200x135.jpg"},"responsive-300":{"file":"Screenshot_20210628_161911-300x202.jpg","width":300,"height":202,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-300x202.jpg"},"responsive-450":{"file":"Screenshot_20210628_161911-450x304.jpg","width":450,"height":304,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-450x304.jpg"},"responsive-600":{"file":"Screenshot_20210628_161911-600x405.jpg","width":600,"height":405,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-600x405.jpg"},"responsive-900":{"file":"Screenshot_20210628_161911-900x607.jpg","width":900,"height":607,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911-900x607.jpg"},"full":{"file":"Screenshot_20210628_161911.jpg","width":981,"height":662,"mime_type":"image\/jpeg","source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911.jpg"}},"image_meta":{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0","keywords":[]}},"post":14122,"source_url":"https:\/\/yaronmargolin.com\/wp-content\/uploads\/2021\/06\/Screenshot_20210628_161911.jpg","_links":{"self":[{"href":"https:\/\/yaronmargolin.com\/index.php?rest_route=\/wp\/v2\/media\/17947"}],"collection":[{"href":"https:\/\/yaronmargolin.com\/index.php?rest_route=\/wp\/v2\/media"}],"about":[{"href":"https:\/\/yaronmargolin.com\/index.php?rest_route=\/wp\/v2\/types\/attachment"}],"author":[{"embeddable":true,"href":"https:\/\/yaronmargolin.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/yaronmargolin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17947"}]}}