דף הבית › כללי › The Three Most Important Supplements for People Over 55 — A Natural and Cautious ApproachBy Yaron Margolin

The Three Most Important Supplements for People Over 55 — A Natural and Cautious ApproachBy Yaron Margolin

פורסם ב ע"י ירון מרגולין — אין תגובות ↓
Oןptimal health through natural balance — free of medications, grounded in a deep understanding of the body’s needs.

Hebrew

Background

As we age, the body's exposure to toxins accumulates. This, often referred to as "organ decline due to aging," leads to a weakening of the body's natural defense systems. Methylation processes slow down, mitochondrial function deteriorates, and susceptibility to degenerative diseases increases. Fatigue, reduced libido, poor concentration, and memory issues become more common.

Supplementation must be precise, natural, and supportive — always in combination with nourishing foods, movement, and sunlight. Avoid harmful supplements such as synthetic vitamin D, statins, and blood pressure drugs, which may further compromise the body’s repair systems.

After age 55, the biological balance changes. Toxins such as TMAO and uremic toxins accumulate. Based on updated research and the clinical experience of kidney recovery expert Yaron Margolin, three supplements stand out as essential:

Ubiquinol is essential after age 50.It declines naturally with age, especially in individuals taking statins, blood pressure meds, or diabetes medications.
  1. Coenzyme Q10 (Ubiquinol form)

Supports: Heart, brain, and cellular energy
Protects: Mitochondria from oxidative damage
Recommended dose: 400–600 mg daily, divided into two doses with fatty food

Ubiquinol is essential after age 50.
It declines naturally with age, especially in individuals taking statins, blood pressure meds, or diabetes medications.

Key References:

Amin et al. (2018). European Journal of Clinical Nutrition, 72(6), 848–854.

Hernandez et al. (2011). Journal of Clinical Lipidology, 5(5), 342–349.

Brazil nuts are a rich natural source of selenium.Selenium is absorbed in the body through transporters located in the ileum—the final segment of the small intestine. Few people know that selenium, when present in its organic form selenomethionine (as found in Brazil nuts), can integrate into the body’s proteins and repair damaged ones. In this form, it plays a key role in regulating and removing misfolded proteins. Photo by Yaron Margolin.
  1. Natural Selenium

Supports: Glutathione production, immune system, anti-aging
Source: 1–2 Brazil nuts per day or 200 mcg selenium from a high-quality supplement

Selenium is critical for the function of glutathione peroxidase, the body’s main detox enzyme.
Low levels of selenium are associated with increased mortality in the elderly.

Key References:

Borg et al. (2012). Journal of Nutrition, 142(10), 1814–1818.

  1. Methylcobalamin (Active Vitamin B12)

Supports: DNA repair via methylation, nervous system function, red blood cell production
Helps with: Mood, fatigue, confusion, memory, and depression

After age 50, B12 absorption decreases significantly due to low stomach acidity, medications, and stress.
Only Methylcobalamin (not Cyano-B12!) is biologically active and safe.

Recommended dose: 1,000–5,000 mcg sublingually per day, or based on lab results
Usually 1,000 mcg is sufficient for daily maintenance.

Key References:

Gomella et al. (2013). Journal of Clinical Neurology, 9(2), 77–81.

Finkelstein et al. (2011). Journal of the American College of Cardiology, 57(3), 339–348.

Priority note:
If symptoms like fatigue, foggy brain, depression, or cardiac issues are present, B12 may move up to the second or even first priority.
If digestion and sunlight exposure are excellent, it can be delayed, but in today’s world, daily supplementation is strongly advised.

Supplements to Avoid

Synthetic Vitamin D — suppresses glutathione, disrupts repair mechanisms, increases calcium load on the kidneys

Synthetic multivitamins

Any supplement containing Cyano-B12 or labeled “regular B12”

Bonus (Optional 4th): Fresh Broccoli Sprouts

Natural source of Sulforaphane — activates NRF2, enhances glutathione production, and supports cellular repair from within.

Only effective if consumed fresh or if the supplement includes the enzyme myrosinase, required for sulforaphane activation.

Recommended dose: 50 grams of fresh sprouts daily
Or a high-quality supplement with both sulforaphane and myrosinase.

Key References:

Fahey et al. (2001). PNAS, 98(19), 10324–10329.

Shapiro et al. (2006). Journal of the National Cancer Institute, 98(4), 270–280.

Final Note:

"In older age, the body doesn't need more chemistry. It needs precision.
Supplements must act like keys — if they don’t fit the lock, they do more harm than good."

Have questions?
Yaron Margolin will be happy to answer — with clarity, care, and no false promises.
Just real knowledge, hope, and a clear path forward.

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    For the avoidance of doubt, consult a physician (who knows in detail the general health of each patient or yours) before using any medicine, food, extract or any exercise. The information on Yaron Margolin's website or the "Healing Presses" website (on Facebook or YARONMARGOLIN.COM), in the above article and in Yaron Margolin's articles are material for thought – philosophy neither recommendation nor public guidance to use or cease to use drugs – no information on this site or anyone You should always consult with a qualified physician or pharmacist regarding pain, bad feeling, or goals and how to use foods, ointments, extracts and even exercises, or other remedies that are mentioned as such

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